Computerised Bioinformatics & Biology is an interdisciplinary Area That Expands & Inures Computerised Methods to Examine Huge Assemblage of Biological data Such as Next Generation Sequencing, Array Designing, Microarray Data Analysis so on.
Bioinformatics is the Application of Information Technology, Used to Generate Methods and Software Tool For getting Knowledge of Biological data or Living Things. It is Used For Solving Biological Problems.
Bioinformatics is helpful for Create and Implements Computer Programs That Gives Access to Handle, Use and Manage the Information. it is Also Helpful to Develop New Algorithms and Statical Measures That Is Very Useful to Access Large Data.
1. Functional Gene Annotations / Genome Annotation:
Gene Annotation is the Action of recognizing the Place of Genes and Entire Coding Zone in a Genome and Find What Those Genes Actually Do.
There Are Three Main Steps For Genome Annotation:
a. Recognize Section of Genome That does not Code For Proteins.
b. Recognise Elements of the Genome, A action Called Gene Prediction.
c. Connect Biological Information to These Elements.
2. Next-generation sequencing (NGS):
It is Fresh Process for Sequencing Genome at High Speed & Less Cost. Next Generation Sequencing Also Called Second Generation Sequencing(SGS) or Massively Parallel Sequencing(MPS). NGS Generate a Large Amount of Sequence Data. NGS Plays Key Role in the Big Y Test From Family Tree DNA & Y Prime, Y-Elite & While Genome Test From Full Genomes Corporation. The Mitochondrial DNA full Series test uses next-generation sequencing technology (NGS).
3. Gene / Orf Prediction:
A Gene/ Orf Prediction is the Element of Reading Frame That Has Capacity to Translated.
4. Genome alignment and Analysis:
In Bioinformatics, Sequence Analysis is the Action of Subject to RNA, & DNA. Methods applied for Sequence Alignment, Searches Opposite Biological Database.
5. Multiple sequence alignment:
MSA is Normally the Alignment of Three Or More than three Biological Sequences of Equal Length, Generally Protein, RNA & DNA.
6. BLAST / BLAT Data Analysis:
Blat is Pairwise Sequence Alignment Algorithm Was Created By Jim Kent At UCSC in the 2000s to Help the Assembly & Notation of Human Genome.
7. Comparative Genomics:
Comparative Genomics is the area of Biological Research in WhichGenomis Characteristics of Distinct Creatures are Compared. The Genomic Characteristics Consist the DNA Sequence, Gene Order, Genes, Regulatory Sequences & Another Genomics Landmark.
8. Bioinformatics Consulting:
Bioinformatrics Consulting is Procedure of High Qualified Expertise in Research Computing that Contains Data Management, Data Analysis & Spreading of High-throughout biomedical data.
9. Microarray Data Analysis:
Microarray Analysis is Used for Explaining the Data Generated from Assessments on DNA, RNA & Protein Microarrays, Which Allow Researchers to Analyse Study the Expression State of Huge Numbers of Gene in Many Cases, an organism's Complete Genome in a Single Test.
10. Bioinformatics Databases and Data mining:
The Biological Database is Classified in Three Ways i.e Sequence Database, Structure Database, & Functional Database.
Data Mining Means to Take Out or Mining Knowledge From Big/Huge Database, Data Mining is Used for Searching New Attractive Designs and Connection in a Large Amount of Data.
a. Functional Gene Annotations / Genome Annotation
b. Gene / Orf Prediction
c. Gene Ontology and Pathway Enrichment Analysis
d. Genome alignment and Analysis
e. Motif Prediction
f. Multiple sequence alignment
g. BLAST / BLAT Data Analysis
h. Comparative Genomics
i. Phylogenetic Analysis
j. Custom array designing for any application,any organism, any sequence
k. Targeted resequencing baits for custom Disease gene panels
l. Microarray Data Analysis
m. NGS Data Analysis
n. Bioinformatics Databases and Data mining
o. Bioinformatics Consulting
In 1970s Scientist Found the DNA Series of Simple Living Life. It is Branch Of Science, Based on Anatomy, Drawing, Function, Progress, and Modification of Genome. Genomics is Complete Study of the Genomes of Creatures. A Genome is Entire Set of Creatures DNA, Containing All of Its Genes. Its Key Task is Find The Complete Series of DNA or Structure of the Molecules that Build the DNA and the Chemical Chain Between The DNA Molecules. DNA Sequencing Knowledge is Not Only Very essential For The Biological Research But Equally Important in Medical, Medicine, Biotechnology & In Forensic Research etc.