MANBABY tells the story of stand-up comic Sal Howard who attempts to show his wife how great a mother she will be, by pretending to be a baby. With the help of his friends, Sal pretends to be transformed into a baby by a potion. The cruel farce succeeds in a strange way. While Sal's wife Dana still doesn't want a baby-- or Sal in her house after the stunt-- she actually enjoyed having the man-baby around the house. She begins a plan to create her own MANBABY-- whether Sal wants it or not. Is this the family that she and Sal always wanted?