About

Single Cell has pioneered a new approach to antibody discovery. Its technology is able to analyze the antibodies and mRNA from individual antibody secreting cells.  Antibodies are rapidly screened against multiple molecules to measure their affinity and specificity, and mRNA from the cognate light and heavy chains are sequenced by Next Generation Sequencing (NGS) technology and correctly paired.  In addition to human and mouse cells, Single Cell’s technology can be applied to any host that concentrates plasma cells in lymphoid tissues.  Founders Chun-Nan Chen and Jim Bowlby integrated advances in multiple disciplines, such as wafer fabrication, molecular biology, precision mechanical engineering, nanotechnology, image processing, NGS, and bioinformatics.  Single Cell’s approach substantially decreases the time and investment needed to discover high quality therapeutic and diagnostic antibodies.