About

Physiologic Instruments is a leading manufacturer of precision electrophysiology equipment for the study of epithelial transport, barrier function, and ion channel activity. Our flagship EasyMount® Ussing Chamber Systems are used by researchers worldwide to measure transepithelial electrical properties in both native tissues and cultured monolayers, enabling reproducible, high-fidelity short-circuit current (Isc) and transepithelial resistance (TER/TEER) measurements.

We serve a global customer base spanning academic research institutions, pharmaceutical and biotechnology companies, clinical laboratories, and government research agencies. Our systems are trusted in critical translational research, including cystic fibrosis drug development, gastrointestinal disease studies, and epithelial barrier integrity assays.

Physiologic Instruments’ product line includes:

EasyMount® Ussing Chambers – Designed for rapid setup, reproducibility, and compatibility with various tissue and cell culture formats.

VCC-Series Voltage-Current Clamps – Precision electronics for measuring and controlling epithelial electrophysiology experiments.

Data Acquisition Systems & Software – Integrated tools for real-time recording, analysis, and export of experimental data.

Perfusion and Gas Control Accessories – Maintain optimal temperature, oxygenation, and pH conditions for live tissue and cell cultures.

Our commitment to quality extends from product design and manufacturing to customer training and support. We provide detailed protocols, technical assistance, and troubleshooting resources to ensure researchers achieve optimal performance and data reliability.

Researchers worldwide cite our equipment in peer-reviewed publications, demonstrating its role in advancing knowledge in areas such as cystic fibrosis, inflammatory bowel disease, drug transport, and epithelial barrier research. Our systems are designed for both cutting-edge research and educational laboratories, offering a balance of flexibility, precision, and durability.

At Physiologic Instruments, we believe in empowering scientists with tools that make experiments more efficient, reproducible, and insightful — so they can focus on scientific discovery, not hardware limitations.

For more information, visit https://www.physiologicinstruments.com