About

Following the sale of its award winning ATF System for cell perfusion, Refine Technology continues to innovate in the fields of cell biology and bioprocessing.  Refine is dedicated to the development of products to fulfill unmet needs and to provide operational efficiencies in many areas of bioprocessing.

The first such product is the CleanLine 1.5" single use connector designed to improve sterile fluid flow rates in large volume single use and hybrid single use bioreactor systems.  As single use bioreactor bags scale up to 2,000 liters or more, the addition of media or the evacuation of fluid from the bags is time consuming when constrained by small connections and tubing.  The CleanLine Connector delivers flow rates of 290 liters/minute which significantly increases process efficiency.  Refine Technology also has the capability to provide fully assembled connector and tubing products to fit specific customer needs.

Refine Technology is also developing a stand alone, mini bioreactor that will operate in the 35-100ml range.  With a compact footprint of only 4" x 8" x 13", it is an excellent choice for small scale experiments and budget conscious laboratories.  The bioreactor has built in controls for all functions and process controls such as DO, pH and temperature via external, optical probes.  The only fluid contact surface is the impeller.  The built in controller also supports up to eight pumps or valves offering a lot of flexibility with experimental design and parameters.

Refine Technology currently operates with two 1,000 to 1,200 square foot ISO Class 7 cleanrooms and has the capability to provide custom clean room assembly services.  The company looks to continue to innovate in the fields of cell biology and bioprocessing and has several more products in the pipeline that are expected to be completed in 2018.